Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage. Although rare, use of acetaminophen has been reported to lead to liver transplantation and death, usually at high doses and when multiple acetaminophen-containing products have been used. Tramadol and acetaminophen combination is used to relieve acute pain severe enough to require an opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. When used together, the combination provides better pain relief than either medicine used alone.
They can also kick active drugs from their connections, reversing an overdose in seconds.8 These medications are commonly used to treat opioid use disorder (OUD). An allergic reaction to tramadol and naproxen is rare. Even so, rare cases of a potentially life-threatening, whole-body allergy called anaphylaxis have been reported. It’s generally safe to sleep after taking Tramadol as prescribed. However, avoid activities requiring full alertness until you understand how Tramadol affects you.
- Always follow the guidance of your healthcare provider when using Tramadol.
- Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.
- If you use tramadol with certain drugs, you may have more side effects.
- When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
Tramadol
- Using too much of this medicine may cause infertility (unable to have children).
- You may need to have blood tests during your treatment with tramadol.
- Tramadol and naproxen (marketed under the brand name Aleve) are two oral painkillers that can be taken together.
- It’s critical to talk with your doctor and pharmacist about your tramadol use and the other medications or substances you take.
- There are no known interactions with tramadol and food.
Severe breathing problems and deaths have been reported in some children who received codeine after tonsil or adenoid surgery. Long-term use of tramadol may affect your ability to become pregnant or get a partner pregnant. Talk with your healthcare provider if you have any concerns. People who are 65 years and older can be at greater risk for some side effects from tramadol.
Tramadol is a prescription painkiller in the opioid class. In 2021, doctors wrote about 30.5 million prescriptions for this drug in the United States.1 Each prescription likely came with a list of instructions, including potential interactions. If you lost yours, you could be missing vital information that could save your life.
You should carry the list with you in case of emergencies. Tramadol may harm or cause death to other people who take your medication, especially children. Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position.
What should I know about storage and disposal of this medication?
This is a big drop from the 40% of people who commonly experience side effects with tramadol. Naproxen tends to cause fewer side effects, although some people are more sensitive to the drug. The risk of side effects is greater if naproxen is overused. Prior to initiating Tramadol, it’s vital to have an open discussion about your medical history and any substances you may be using with your healthcare provider. Adhering closely to their guidance and refraining from self-medication is paramount for ensuring your safety.
Drugs you should not use with tramadol
Consult a healthcare provider if you suspect a UTI for proper diagnosis and treatment. You may need to have blood tests during your treatment with tramadol. The cost of these tests will depend on your insurance coverage.
Naproxen
Long-term use of tramadol can cause your body’s adrenal glands to stop making as much cortisol (the stress hormone). Adrenal insufficiency can get worse if your body is under stress because of fever, surgery, or trauma. Tell your healthcare provider if you have any of the following symptoms of adrenal insufficiency. The most common side effects of tramadol are Tramadol interactions listed below. Tell your healthcare provider if you have any of these side effects that bother you. Tramadol works in the brain to change how your body feels and responds to pain.
Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. When tramadol was used in children, serious and life-threatening breathing problems such as slow or difficulty breathing and deaths were reported. Several opioids, such as oxycodone, morphine, and hydromorphone, are considered stronger pain relievers than Tramadol. These medications are usually reserved for severe pain but come with a higher risk of dependence and side effects. Always follow healthcare provider recommendations for pain management. Do not change the dose or suddenly stop taking this medicine without first checking with your doctor.
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Tramadol is a medication that belongs to the class of drugs known as opioid analgesics. It is commonly used to treat moderate to moderately severe pain. Tramadol works by binding to opioid receptors in the brain and spinal cord to ease the pain.
It works by changing the way the brain and nervous system respond to pain. This medicine may cause serious allergic reactions, including anaphylaxis, angioedema, or certain skin conditions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis). These reactions can be life-threatening and require immediate medical attention.
Tramadol, Oral Tablet
Do not drink alcohol, take prescription or nonprescription medications that contain alcohol, or use street drugs during your treatment. Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). Tramadol is a popular medication prescribed for moderate to severe pain relief, functioning as a central nervous system depressant to alter the perception of pain. Learn more, and contact The Edge Treatment Center if you have any questions. These may be symptoms of a serious condition called serotonin syndrome.





